Yellow Fever

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Yellow fever is caused by yellow fever virus, an enveloped RNA virus 40–50 nm in width, the type species and namesake of the family Flaviviridae. It was the first illness shown to be transmissible by filtered human serum and transmitted by mosquitoes, by American doctor Walter Reed around 1900. The positive-sense, single-stranded RNA is around 10,862 nucleotides long and has a single open reading frame encoding a polyprotein. Host proteases cut this polyprotein into three structural (C, prM, E) and seven nonstructural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5); the enumeration corresponds to the arrangement of the protein coding genes in the genome. Minimal yellow fever virus (YFV) 3'UTR region is required for stalling of the host 5'-3' exonuclease XRN1. The UTR contains PKS3 pseudoknot structure, which serves as a molecular signal to stall the exonuclease and is the only viral requirement for subgenomic flavivirus RNA (sfRNA) production. The sfRNAs are a result of incomplete degradation of the viral genome by the exonuclease and are important for viral pathogenicity. Yellow fever belongs to the group of hemorrhagic fevers.

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WHO: Yellow fever outbreak is ‘serious and of great ...
WHO: Yellow fever outbreak is ‘serious and of great ...
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Yellow fever - Wikipedia
Yellow fever - Wikipedia
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UN bungles response to Africa’s yellow fever outbreak ...
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Yellow Fever’s Comeback Was Utterly Avoidable, But We Blew ...
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Yellow fever - Wikipedia
Yellow fever - Wikipedia
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Yellow Fever's Comeback Was Utterly Avoidable, But We Blew ...
Yellow Fever's Comeback Was Utterly Avoidable, But We Blew ...
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Brazil Yellow Fever Outbreak Persists Although Number of ...
Brazil Yellow Fever Outbreak Persists Although Number of ...
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Going Viral | The Center for International and Security ...
Going Viral | The Center for International and Security ...
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10 Diseases Which Threaten To Wipe Out Humanity – Page 6 ...
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Mr. LaRose's Language Arts Discussion Board
Mr. LaRose's Language Arts Discussion Board
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Yellow Fever is Back. How Worried Should We Be? | UN Dispatch
Yellow Fever is Back. How Worried Should We Be? | UN Dispatch
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पित्त ज्वर और इसका घरेलु इलाज Yellow Fever Symptoms Causes ...
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How to Get the Yellow Fever Vaccine
How to Get the Yellow Fever Vaccine
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US officials keep watchful eye on yellow fever outbreak in ...
US officials keep watchful eye on yellow fever outbreak in ...
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What Is Yellow Fever? | Causes, Protection & Prevention
What Is Yellow Fever? | Causes, Protection & Prevention
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Yellow fever concept background — Stock Photo © ellandar ...
Yellow fever concept background — Stock Photo © ellandar ...
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Yellow Fever in 7 Nigeria States - Why Vaccination is ...
Yellow Fever in 7 Nigeria States - Why Vaccination is ...
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A Small Guide To Recognize And Treat Yellow Fever - Health ...
A Small Guide To Recognize And Treat Yellow Fever - Health ...
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Infectious Disease Fridays: #IDFridays Week 6: Yellow Fever
Infectious Disease Fridays: #IDFridays Week 6: Yellow Fever
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Yellow fever outbreak in Congo could go global - Business ...
Yellow fever outbreak in Congo could go global - Business ...
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Yellow Fever Outbreak In Brazil Has Ended With 261 Deaths ...
Yellow Fever Outbreak In Brazil Has Ended With 261 Deaths ...
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WHO dispatched 3.5 million doses of yellow fever vaccine ...
WHO dispatched 3.5 million doses of yellow fever vaccine ...
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EMSS | International Travel and the Urban Spread of Yellow ...
EMSS | International Travel and the Urban Spread of Yellow ...
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Guyanese seeks joint effort with Brazil for 100% Yellow ...
Guyanese seeks joint effort with Brazil for 100% Yellow ...
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IAMAT | Yellow Fever
IAMAT | Yellow Fever
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Yellow Fever Maps
Yellow Fever Maps
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